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Pantone Color Manager 2 1 Crack Zipl. Image with no alt text. DOWNLOAD: 7c7a807c3a. Related. pantone color manager download, pantone color manager software, pantone .Non-refractory or refractory B lymphoblastic leukaemia, acute lymphoblastic leukaemia (ALL) and acute myeloid leukaemia (AML) are diagnosed on the basis of the immunophenotype of their leukaemic blast cells.
Primary ALL blasts typically express CD19, CD10, sIgmu, and CD22, in addition to CD34 and CD19; whereas ALL blasts in relapse express CD19, CD10, CD34, and CD38. Secondary ALL blasts express CD34 and CD19, but not CD10 or sIgmu; whereas CD34 and CD19 are expressed, but CD10 and CD22 are typically absent.
AML blasts express CD13, CD33, and CD117, in addition to CD14, CD11c, CD2, CD3, CD4, CD11b, CD19, and CD20.
The aim of this study was to assess the sensitivity and specificity of the immunophenotype of leukaemic blast cells in discriminating between ALL and AML.
Twenty-eight patients with ALL and 16 patients with AML were included in this study.
Immunophenotyping of blasts was performed using dual-colour flow cytometry, including panels of monoclonal antibodies specific for CD3, CD4, CD8, CD16, CD22, CD34, CD38, CD45, CD56, CD117, CD123, CD14, CD15, and cytoplasmic κ and λ light chains.
The data were analysed using univariate methods, and the following results were found:
Although no differences in the results of immunophenotyping were found between ALL and AML patients at diagnosis, discrepancies were found between the diagnostic immunophenotype of blasts and that at relapse in ALL patients.
In ALL patients at diagnosis, secondary relapses expressed mainly CD19 and CD10, whereas primary relapses expressed only